Protection against Pneumocystis carinii pneumonia by antibodies generated from either T helper 1 or T helper 2 responses
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چکیده
منابع مشابه
Protection against Pneumocystis carinii pneumonia by antibodies generated from either T helper 1 or T helper 2 responses.
To determine whether different antibody isotypes associated with T helper 1 (Th1) or Th2 responses are protective against Pneumocystis carinii, mice with disrupted interleukin 4 genes (IL-4(-/-) mice) or gamma interferon genes (IFN-gamma(-/-) mice) along with wild-type C57BL/6 mice were immunized intratracheally against P. carinii, depleted of T cells in vivo by use of monoclonal antibodies, an...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1997
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.65.12.5052-5056.1997